Cymbalta side effects

Although not all of these side effects side may occur, if side they do occur they may need medical attention. In these studies, the effects effects most common effects side effects side of Cymbalta included: Nausea - occurring in side up to cymbalta 25 percent of people. Drowsiness - in cymbalta up to cymbalta 12 percent. Ref Uncommon (0.1 to 1 cymbalta side effects cymbalta Acute liver injury, elevated liver enzymes (ALT, AST, GGT, alkaline phosphatase hepatitis, increased blood bilirubin Rare (less than.1 effects Hepatic failure, jaundice Ref Hypersensitivity Postmarketing reports : Anaphylactic reaction, hypersensitivity Ref Immunologic Common (1. Ref Common (1 cymbalta to 10 Pruritus, hyperhidrosis Uncommon (0.1 to 1 Cold sweat, contact dermatitis, erythema, increased tendency to bruise, night sweats, photosensitivity reaction, urticaria Rare (less than.1 Angioneurotic edema, ecchymosis, Stevens-Johnson syndrome Postmarketing reports : Erythema multiforme, petechiae, cutaneous vasculitis. This medication may raise your side blood pressure. It has cymbalta been suggested that effects there is a dose-related effect cymbalta in the development of hyponatremia effects with cymbalta duloxetine. An increased risk of suicidal thinking and effects behavior in children, adolescents, and effects young adults (aged 18 to 24 years) with effects major depressive disorder (MDD) and effects other psychiatric disorders has been reported with short-term use of antidepressant drugs. Some of the dosage forms listed on this page may not apply to the brand name, cymbalta. Some of the rare Cymbalta side effects include canker sores, high cholesterol, and acne. A very serious allergic reaction to this drug is rare. See also Warning section. Some of the most common side effects of Cymbalta can include nausea, drowsiness, cymbalta and dizziness. Get medical help right away if you have cymbalta effects any very serious side effects, including: black/ bloody stools, vomit that looks like coffee grounds, seizure, eye pain /swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night, blurred vision ). Other side effects include: agitation, effects erectile dysfunction, nervousness, psychomotor agitation, tension, vomiting, abdominal pain, anorexia, decreased appetite, decreased libido, hyperhidrosis, cymbalta generic loss of libido, and restlessness. In Canada - Call your effects doctor for effects medical advice about side effects. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. Remember that your doctor has prescribed this medication because he or effects she has judged that the benefit to you is greater than the risk of side effects. Check your blood pressure regularly and tell side your doctor if the results are high. Ref Other Falls were reported more commonly in patients 65 years of age or older. Hyponatremia tends to develop within the first few weeks of treatment (range 3 to 120 days) and typically resolves within 2 weeks (range 48 hours to 6 weeks) after therapy has been discontinued with some side patients requiring treatment (e.g., water restriction, dietary sodium). You may report side effects to FDA at 1-800-FDA-1088 or at www. Medical Disclaimer Next Dosage More about Cymbalta (duloxetine) Related treatment guides. Diarrhea - in up to 10 percent. Ref Psychiatric side Antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Ref Common (1 to 10 Abnormal orgasm/anorgasmia, decreased libido, delayed ejaculation, ejaculation disorder, erectile dysfunction, urinary frequency Uncommon (0.1 to 1 Abnormal urine odor, dysuria, gynecological hemorrhage, menopausal symptoms, micturition urgency, nocturia, cymbalta pollakiuria, polyuria, sexual dysfunction, testicular pain, urinary hesitation. Some side effects may not be reported. Kruger S, Lindstaedt M "Duloxetine and hyponatremia: a report of 5 cases." J Clin Psychopharmacol 27 (2007. In the US - Call your doctor for side medical advice about side effects. You may report side effects to Health Canada. Ref Very common (10 or more Insomnia Common (1 to 10 Abnormal dreams, agitation, anxiety, sleep disorder Uncommon (0.1 to 1 Apathy, bruxism, disorientation/confusional state, irritability, mood swings, nervousness, poor quality sleep, suicide attempt Rare (less than.1 Aggression and anger, completed. Maramattom BV "Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures." Neurology 66 (2006 773-4. Common side effects of Cymbalta include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea, sedated state, headache, and xerostomia. Sweating - in up to 7 percent. This is not a complete list of possible side effects. Ref Common (1 to 10 Blurred vision Uncommon (0.1 to 1 Diplopia, dry eye, mydriasis, visual impairment Rare (less than.1 Glaucoma Ref Renal Postmarketing reports : Renal impairment Ref Respiratory Common (1 to 10 Cough, nasopharyngitis, oropharyngeal pain, pharyngolaryngeal pain. "UK Summary of Product Characteristics." O. (This article covers many, but not all, of the possible side effects with Cymbalta. Many people side using this medication do not have serious side effects. Loss of appetite - in up to 9 percent. Common Side Effects of Cymbalta, cymbalta has been studied thoroughly in clinical trials in which the side effects of a group of people taking the drug are documented and compared to another group not taking the medicine. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe effects dizziness, severe nausea/ vomiting / side diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness. Cymbalta ( duloxetine hydrochloride). However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat severe dizziness, trouble breathing, skin blisters, mouth cymbalta sores. Numerous effects cases of hyponatremia have been reported following treatment with an ssri. The proposed mechanism for the development of hyponatremia involves the syndrome of inappropriate secretion of antidiuretic hormone (siadh) via release of antidiuretic hormone. The risk increases if you are also taking other drugs that increase cymbalta side effects serotonin, so tell your doctor or pharmacist of all the drugs you take (see side Drug Interactions section). Check with your doctor immediately if any of the following side effects occur while taking duloxetine: Incidence Not Known, abdominal or stomach pain area rash blindness blistering, peeling, or loosening of the skin blurred vision change in consciousness chills clay-colored. You may report them to the FDA. For the Consumer, applies to duloxetine : oral side capsule, oral capsule delayed release. Causality has not been established. The majority of cases were reported in patients with past or current risk factors for liver injury, including alcohol abuse, hepatitis, or exposure to drugs with known adverse effects on the liver. Dizziness - in up to 10 percent. Tell your doctor right away if any of these serious side effects occur: confusion, easy bruising/bleeding, decreased interest in sex, changes in sexual ability, muscle cramps / weakness, shaking (tremor difficulty effects urinating, signs of liver problems (such as stomach / abdominal. However, not everyone who takes Cymbalta will experience side effects. Fatigue - in up to 11 percent. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Ref Gastrointestinal Case side reports and epidemiological studies (case-control and cohort design) have demonstrated an association between the use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleeding. If any of these effects persist or worsen, tell your doctor promptly. In fact, most people tolerate the medication well. Along with its needed effects, duloxetine (the active ingredient contained. Dry mouth - in up to 15 percent (see, cymbalta and Dry Mouth headaches - in up to 14 percent. Generic Name: duloxetine, note: This document contains side effect information cymbalta about duloxetine. "Australian Product Information." O. Other common Cymbalta side effects (occurring in 2 to 5 percent of people) included: Cymbalta Side Effects Article Continues on Next Page. Cymbalta Side Effects: An Introduction, as with any medicine, there are possible side effects with. Check with your health care professional if any of the following side effects continue or are bothersome side or if you have any questions about them: More Common Body aches or pain cough difficulty having a bowel movement (stool) dry mouth ear. Ref Common (1 to 10 Flushing, hot flush, hypertension, increased blood pressure, palpitations Uncommon (0.1 to 1 Chest pain, myocardial infarction, orthostatic hypotension, peripheral coldness, tachycardia Rare (less than.1 Hypertensive crisis, supraventricular arrhythmia (mainly atrial fibrillation ) Postmarketing reports : Hematomas. Aggression and anger have been reported particularly early in treatment or after treatment discontinuation. Adult and pediatric patients receiving antidepressants for MDD, cymbalta as well as for psychiatric and nonpsychiatric indications, have reported symptoms that may be precursors to emerging suicidality, including anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia, hypomania, and mania. Cymbalta (duloxetine)." Lilly, Eli and Company, Indianapolis,. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or lying position. Ref Very common (10 or more Constipation, diarrhea, dry mouth, nausea Common (1 to 10 Abdominal pain, dyspepsia, flatulence, vomiting Uncommon (0.1 to 1 Dysphagia, eructation, gastritis, gastroenteritis, gastrointestinal hemorrhage, halitosis, hematochezia, stomatitis Rare (less than.1 Gastric ulcer Postmarketing reports : Gastrointestinal. These side effects may go away during treatment as your body cymbalta adjusts to the medicine. When Cymbalta side effects do occur, in most cases they are minor and either require no treatment or can be easily treated by you or your healthcare provider. Cymbalta ) may cause some unwanted effects. See below for a comprehensive list of adverse effects. Nausea, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. Risk factors include advanced age, female effects gender, concomitant use of diuretics, low body weight, and lower baseline serum sodium levels. Safdieh JE, Rudominer R "A case of hyponatremia induced by duloxetine." J Clin Psychopharmacol 26 (2006 675-676 Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Your healthcare provider can discuss a more complete list of Cymbalta side effects with you.). In one case report, duloxetine induced hyponatremia was confirmed after inadvertent rechallenge. Dizziness or lightheadedness may occur, especially when you first start or increase your dose of this drug. However, there are several side effects that you should effects report to your healthcare provider, including a fast heart rate, suicidal thoughts, and hallucinations. If you notice other effects not listed above, contact your doctor or pharmacist. Dirks AC, van Hyfte DM "Recurrent hyponatremia after substitution of citalopram with duloxetine." J Clin Psychopharmacol 27 (2007 313. Ref Very common (10 or more Fatigue Common (1 to 10 Asthenia, chills/rigors, pyrexia, vertigo Uncommon (0.1 to 1 Ear pain, falls, feeling abnormal, feeling hot and/or cold, malaise, thirst, tinnitus Ref Cardiovascular Orthostatic hypotension and syncope tend. In many cases, side effects are minor and may be easily treated by you or your healthcare provider. Abdominal pain (stomach pain) - in up to 6 percent. Insomnia - in up to 10 percent (see, cymbalta and Insomnia constipation - in up to 10 percent. This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome /toxicity. The risk of blood pressure decreases may be greater when duloxetine (the active ingredient contained in Cymbalta ) is given concomitantly with drugs that may induce orthostatic hypotension, such as antihypertensives, with potent CYP450 1A2 inhibitors, or with duloxetine doses above 60 mg per day. Note: This document contains side effect information about duloxetine. Some of the dosage forms listed on this page may not apply to the brand name. Common side effects of, cymbalta include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea. Cymbalta, side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug. Cymbalta is used to treat depression, cymbalta weight gain OCD, and fibromyalgia, in addition to other conditions. But like all drugs, it can come with dangerous consequences. Cymbalta side effects you. A: According to the prescribing information for. Cymbalta (duloxetine increased cholesterol levels have been reported with its use, but this is an infrequent side effect. Weight gain is a common. Duloxetine is used to treat depression and addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical. The most common side effects of duloxetine are nausea, dry mouth, constipation, diarrhea, fatigue, difficulty sleeping, and creased blood pressure can occur and should be monitored. Cymbalta, side Effects and Warnings. While there is a significant danger associated with getting off. Cymbalta, there is also the potential for negative effects while. Common Side Effects. Cymbalta Cymbalta has been studied thoroughly in clinical trials in which the side effects of a group of people taking the drug are documented and compared to another group not taking the medicine. Use the dropper provided to remove the required amount of zoloft oral solution and mix with 4 ounces (1/2 cup) of water, ginger ale, lemon/lime soda, lemonade or orange juice only. Zoloft administered in the late luteal phase of the menstrual cycle was statistically significantly more effective than placebo on change from baseline to endpoint on the drsp total score and the CGI-S score, as well as the CGI-I score at endpoint (Week 12). OCD : three short-term trials in adults and one short-term trial in pediatric patients See Clinical Studies.

Cymbalta high

Rx Only m Lilly Cymbalta duloxetine hydrochloride capsule, delayed release Product Information cymbalta Product Type human prescription drug label Item Code (Source) NDC: Route of high Administration oral DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Duloxetine hydrochloride (Duloxetine) Duloxetine. Respiratory, Thoracic and Mediastinal Disorders Frequent: yawning, oropharyngeal cymbalta pain; Infrequent: throat tightness. Depression and other serious mental illnesses are the most important causes cymbalta of suicidal thoughts or actions. Do not high stop using Cymbalta without first cymbalta talking cymbalta side effects to high your doctor. Steady-state plasma concentrations are typically achieved after 3 days cymbalta of dosing. The 20 and 60 mg capsules also contain iron oxide high yellow. Cymbalta should be discontinued in cymbalta patients who develop jaundice or other evidence of clinically significant liver dysfunction and should not be resumed unless another cause can be established. Hyponatremia Advise patients that hyponatremia has been reported as a result of treatment with snris cymbalta and ssris, including Cymbalta. After 7 weeks of treatment with Cymbalta 60 mg once daily, in OA-1 patients with sub-optimal response to treatment ( 30 pain reduction) and tolerated Cymbalta 60 mg once daily had their dose increased to 120 mg. Pediatric Use Safety and efficacy of Cymbalta in patients 7 to 17 years of age have been established for the treatment of GAD. Reproductive System and Breast Disorders Frequent: anorgasmia/orgasm abnormal; Infrequent: menopausal symptoms, sexual dysfunction, and testicular pain; Rare: menstrual disorder. Laboratory Tests No specific laboratory tests are recommended. Cymbalta can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. Furthermore, behaviors consistent with increased reactivity, such as increased startle response to noise and decreased habituation of locomotor activity, were observed in pups following maternal exposure to 30 mg/kg/day. Antidepressant medicines have other side effects. Effect on Blood Pressure In adult placebo-controlled clinical trials across indications from baseline to endpoint, Cymbalta treatment was associated with mean increases.5 mm Hg in systolic blood pressure and.8 mm Hg in diastolic blood pressure compared to mean. Cases with serum sodium lower than 110 mmol/L have been reported and appeared to be reversible when Cymbalta was discontinued. Always consult your healthcare provider to ensure the information displayed on this page applies cymbalta side effects to your personal circumstances. Severe Skin Reactions Severe skin reactions, including erythema multiforme and Stevens-Johnson Syndrome (SJS can occur with Cymbalta. Counsel patients to call their doctor cymbalta right away or get emergency help if high they have skin blisters, peeling rash, sores in their mouth, hives, or any other allergic reactions see Warnings and Precautions (.6 ).

What is cymbalta used for

The researchers noted that use of Cymbalta what could result in fewer side effects than the drugs traditionally used for the condition, such as non-steroidal anti-inflammatory drugs, or nsaids, which can lead to what gastrointestinal bleeding, and what opioids like morphine, which often used lead to constipation. Adverse Reactions Observed In Children And Adolescent Placebo-Controlled Clinical Trials The adverse drug reaction profile observed in pediatric clinical trials (children and adolescents) was consistent with the adverse drug reaction profile observed in adult clinical trials. Retrieved from.gov/pmc/articles/PMC3056054/ FDA. Cardiac Disorders Frequent: for palpitations ; Infrequent: myocardial infarction and tachycardia. General Disorders and Administration Site Conditions Frequent: chills/rigors; Infrequent: falls, feeling abnormal, feeling hot and/or cold, malaise, and thirst; Rare: gait disturbance. Cymbalta for could also what help ease pain associated with osteoarthritis, according to a study published in the International Journal of Clinical Practice in 2012. Tell your doctor for if you what are breast-feeding. You'll receive a coupon by email or text to get the best price at a local participating pharmacy near you. Other signs to look for are elevated blood pressure, heavy sweating and rapid heart rate. Generalized Anxiety Disorder, approximately.7 (139/1018) of the patients who received cymbalta in placebo-controlled trials for GAD discontinued treatment due to an adverse reaction, compared with.0 (38/767) for placebo. Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes ( diabetic neuropathy ). FDA clears Cymbalta to treat chronic musculoskeletal pain. FDA Warnings, Reviews and Reprimands The FDA has become increasingly aware of risks and side effects associated with Cymbalta use. The agency, for example, used required labels what of antidepressant drugs, including Cymbalta, to include a black box warning, the agencys strictest warning, regarding the risk of suicidal thinking and behavior in children, adolescents and adults. What should I avoid while taking duloxetine (Cymbalta, Irenka)? Cymbalta is the brand name for duloxetine, an antidepressant prescribed to treat the symptoms of depression. The drugs label instructs patients: Take Cymbalta once daily, with or without food If you miss a dose, take the missed dose as soon as you remember If it is almost time for the next dose, skip. The most common (5 and twice placebo) adverse reactions observed in pediatric clinical trials include: nausea, diarrhea, decreased weight, and dizziness. Be used careful if you drive or do anything that requires you to be alert. Musculoskeletal and Connective Tissue Disorders Frequent: musculoskeletal pain; Infrequent: muscle tightness and muscle twitching. Food what and Drug Administration (FDA) first approved Cymbalta in 2004. Nervous System Disorders Frequent: dysgeusia, lethargy, and paraesthesia/hypoesthesia; Infrequent: disturbance in attention, dyskinesia, myoclonus, and poor quality sleep; Rare: dysarthria. Approximately.9 (117/906) of the patients who received cymbalta in placebo-controlled trials for dpnp discontinued treatment due to an adverse reaction, compared with.1 (23/448) for placebo. Psychotherapy for Depression ) are often used along with antidepressant medication to treat depression. Chronic Pain what due To Osteoarthritis, approximately.7 (79/503) of the patients who received cymbalta in 13-week, placebo-controlled trials for chronic pain due to OA discontinued treatment due to an adverse reaction, compared with.3 (37/508) for placebo. Use this drug with caution what if you have certain medical conditions. Counseling and therapy (see. Gastrointestinal Disorders Frequent: flatulence ; Infrequent: dysphagia, eructation, gastritis, gastrointestinal hemorrhage, halitosis, and stomatitis; Rare: gastric ulcer. At its peak in 2013, Cymbalta had annual sales of 5 billion. Neurotransmitters, including serotonin, dopamine and norepinephrine pass signals between nerve cells. Store Cymbalta at room temperature away from moisture and heat. Advisory Committee Review Because of reports of serious side effects like liver damage and skin disease, an FDA advisory committee met in 2010 to review whether or not the benefits outweighed the risks in the use of Cymbalta for treating chronic pain. You may take duloxetine with or without food. Cymbalta 20mg capsule, cymbalta 30mg capsule, cymbalta 60mg capsule. Fibromyalgia, the most commonly observed adverse reactions in cymbalta-treated patients (as defined above) were nausea, dry mouth, constipation, somnolence, decreased appetite, hyperhidrosis, and agitation. The Food and Drug Administration (FDA) approved duloxetine in 2004 under the brand name Cymbalta for the Lilly drug company. What happens if I overdose (Cymbalta, Irenka)?

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